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ConditionsKRA

Kratom Use Disorder

A plant from Southeast Asia that acts on opioid receptors. Sold in smoke shops in the U.S.

What to know. Withdrawal resembles opioid withdrawal; can be managed with medication.

First-line care
Buprenorphine, naltrexone, or Vivitrol (long-acting naltrexone)

What major medical bodies recommend first when this condition is the focus of care.

Off-label medications can be used in addition to behavioral therapy.


Symptoms

How clinicians think about it.

The DSM-5 lists eleven signs grouped into four areas. The number that fit in the past year suggests a severity — not a verdict.

LOSS OF CONTROL · 4
  • ·Using more than meant to
  • ·Wanting to cut down
  • ·Time spent using
  • ·Cravings
SOCIAL IMPACT · 3
  • ·Trouble at work / school
  • ·Relationship strain
  • ·Giving up activities
RISKY USE · 2
  • ·Risky situations
  • ·Using despite harm
PHYSICAL · 2
  • ·Tolerance
  • ·Withdrawal

Risks worth knowing

Plainly: what makes this condition dangerous.

Moderate concern

Opioid-like withdrawal (sweats, muscle aches, anxiety)

High concern

Adulterated products of unknown potency

Lower concern

Liver injury — rare but reported


Treatment options

What's offered, and what we usually start with.

FIRST-LINE — RECOMMENDED FIRST
01
BuprenorphineFirst-line

Treats kratom withdrawal effectively. Often a shorter course than for OUD.

02
NaltrexoneFirst-line

Daily oral pill that blocks opioid receptors. For people who have completed withdrawal.

03
Vivitrol (extended-release naltrexone)First-line

Monthly injection of naltrexone. A once-a-month option that doesn't depend on remembering daily pills.

04
Symptomatic management

Clonidine, anti-nausea, sleep support during taper.


Common questions

Asked often, answered briefly.

Natural doesn't mean harmless. Kratom binds the same brain receptors as opioids. Many people use it without trouble; some develop dependence and need help to stop.

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This is not a diagnosis. These tools are for reflection and conversation. A clinician's evaluation is the only way to confirm a substance use disorder. If you are in crisis, call or text 988.
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